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The Science of N=1
Why the 'Gold Standard' of clinical trials fails the individual, and why true precision health treats you as a single-subject experiment.

In modern science, the Randomized Controlled Trial (RCT) is worshipped as the "Gold Standard." To prove a drug works, you give it to 1,000 people. If 600 improve and 400 don't, the drug is deemed "effective."
That's great for the pharmaceutical company. They can sell it to everyone. But what if you are one of the 400?
For you, that "effective" drug is 0% effective. In fact, it might be toxic.
The Tyranny of the Average
Traditional Evidence-Based Medicine (EBM) relies on aggregates. It smoothes out the data to find the "average patient."
But biology doesn't work on averages. Biology works on specificity.
- Nutritional Individuality: A 2015 study by the Weizmann Institute showed that two people can eat the exact same banana, and one will have a massive blood sugar spike while the other stays flat. No "average" diet can predict this.
- Biomechanical Variance: Two runners with the same shoe size might have completely different kinetic chains. One needs stability; the other needs freedom. The "average" shoe fails both.
The New Paradigm: N=1
At MorphoLab, we subscribe to a different scientific philosophy: The N=1 Experiment.
In an N=1 trial, the sample size is one. You. We don't care what works for "most people." We care what works for this specific biological system, with this specific history, in this specific environment.
- We measure your unique data (scan, gait, pressure).
- We intervene with a custom solution (not a size 9, but your shape).
- We feedback based on your results.
Beyond Footwear
This philosophy is the foundation of everything we do, and everything we will do.
Today, it's about custom biomechanics. Tomorrow, it will be about Precision Supplementation. Why take a multivitamin formulated for the "average adult male" when we can analyze your blood work and print a daily stack that contains exactly—and only—what your body lacks?
The future of health isn't finding the cure for the masses. It's finding the optimization for the individual. You are not a statistic. You are a sample size of one.